Oligodendrogenesis after Cerebral Ischaemia and Traumatic Brain Injury

Oligodendrogenesis after Cerebral Ischaemia and Traumatic Brain Injury

Blog Article

Teaset Stroke and traumatic brain injury (TBI) damage white and grey matter.Loss of oligodendrocytes and their myelin, impairs axonal function.Remyelination involves oligodendrogenesis during which new myelinating oligodendrocytes are generated by differentiated oligodendrocyte progenitor cells (OPCs).

This article briefly reviews the processes of oligodendrogenesis in adult rodent brains, and promising Cat Beds experimental therapies targeting the neurovascular unit that reduce oligodendrocyte damage and amplify endogenous oligodendrogenesis after stroke and TBI.